Polymethyl methacrylate was developed by the German chemist O. Rohn in 1902 and patented in 1928 as “Plexiglas”. Since then it has been used for various purposes in industry, dentistry and medicine (as bone cement, it is used for fixing artificial joints. PMMA specially prepared for this purpose fills the space between the prosthesis and the bone).
In the filling of lips, grooves, cheekbones, scars, wrinkles, etc. Facial fillers with a revolutionary non-surgical method within medical aesthetics, intended to correct facial contour deformities without surgery, such as wrinkles, folds and scars, or to model or fill structures, such as the lips and cheekbones. It is applied in furrows (eg: nasolabial folds), wrinkles, chin, cheekbones, lip filler, small nose corrections, scars, etc.
It is VERY IMPORTANT to clarify that in Argentina, the ANMAT (National Administration of Medicines, Food and Medical Technology) has approved it for certain indications of use. The indications for use approved by ANMAT must be strictly respected by doctors.
PMMA or polymethylmethacrylate spheres have a smooth and homogeneous texture. Once the product is applied, the spheres are permanently deposited in the tissues. Due to their size, shape and softness, they cannot be phagocytized or eliminated by the cells of the human immune system, nor can they be drained by the lymphatic system.
After 1 to 3 months of its application, the spheres are completely surrounded by the body’s own collagen, resulting in a lasting and definitive correction or increase. Studies have observed that histologically, there are no observable changes in the tissue after 4 years of its placement, from which it can be deduced that it is a long-lasting treatment.
The correction of defects where PMMA is used is instantaneous, painless and definitive and does not present complications in most cases when it is used by doctors duly trained for it.
The duration is definitive and permanent, since it is a non-resorbable product, unlike other temporary resorbable fillers such as hyaluronic acid, collagen, etc.